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能操控人类思想的寄生虫

我们人类珍视我们的自由意志和独立,但是有一些暗中操控被我们所忽略。作为科普作家,勇埃德在这个吸引人,幽默,并令人不安的演讲中,令人信服地解释了寄生虫对于操控艺术的升华。但是寄生虫也在操控我们么?这真的很有可能。

2015-11-20 课时:14分钟

研究寄生虫的质体,提供药物开发的新靶点

David Roos (U Penn) Part 2: The apicomplexan plastid

Antibiotics are effective because they kill bacteria without harming humans and other eukaryotes (organisms with cells that contain nuclei). So why are the eukaryotic parasites responsible for malaria and toxoplasmosis killed by drugs like clindamycin? Multidisciplinary studies integrating molecular genetics, cell biology, biochemistry, pharmacology and computational genomics reveal that such drugs target an unusual organelle. The "apicoplast" was acquired when an ancestral organism 'ate' a eukaryotic alga, and retained the algal plastid -- a relative of plant chloroplasts derived from a bacterial ancestor. Although no longer photosynthetic, the apicoplast is essential for parasite survival, providing new targets for drug development. See more at http://www.ibioseminars.org

2016-03-25 课时:33分钟