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间充质干细胞:一把双刃剑,在调节免疫反应

间充质干细胞(MSCs)是在机体内广泛存在的一种具有多向分化潜能的组织干细胞。更由于其具有重要的免疫调节作用而受到重视,近些年来在疾病模式动物模型和临床研究上MSCs被尝试应用于治疗免疫紊乱疾病。尽管有不少文章报道称MSCs有非常良好的治疗效果,但是其治疗适应症、诊疗时机选择和作用机制等有待进一步研究。

2015-02-28 课时:34分钟

免疫反应的细胞基础 - Ira Mellman P1

本视频由科普中国和生物医学大讲堂出品

Ira Mellman (Genentech) Part 1: Cellular Basis of the Immune Response

The immune system is charged with protecting us from invading microorganisms, a task that falls to a complex array of highly specialized cell types spread throughout the body but that must work together as an integrated system. How they accomplish and perform their functions can be wonderfully understood by probing the basic mechanisms governing their activities. In the first video, we will consider the overall organization of the immune response in cellular terms, the innate immune system (comprising evolutionarily ancient phagocytic cells that recognize conserved molecules of microorganisms) and the adaptive immune system (composed of lymphocytes that recognize chemically diverse antigens).

2015-12-14 课时:39分钟

胡洪波:泛素化和非经典NF-kB信号通路在免疫反应和肿瘤免疫中的功能

介绍了泛素化相关作用等,提到了非NF-Kb信号通路与免疫反应、肿瘤免疫之间的关系等。

2017-09-28 课时:45分钟